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An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO2(NO3)2·6H2O under heterogeneous conditions

✍ Scribed by Vardhineedi Sri Venkata Satyanarayana; Amaravadi Sivakumar


Book ID
111491469
Publisher
Versita
Year
2011
Tongue
English
Weight
204 KB
Volume
65
Category
Article
ISSN
0366-6352

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✦ Synopsis


Abstract

An efficient, convenient, and novel one-pot method of 2,4,5-triaryl-1H-imidazoles synthesis using benzil, arene carbaldehydes, and ammonium acetate, catalyzed by uranyl nitrate hexahydrate [UO2(NO3)2·6H2O] supported on acidic alumina and resulting in good to excellent yields under heterogeneous conditions, is reported. Formation of a reactants-catalyst complex was confirmed by UV-VIS spectral data. Antibacterial (MIC) and antioxidant activity of the synthesized compounds was also studied.


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