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An Efficient and General Method for the Synthesis of α,ω-Difunctional Reduced Polypropionates by Zr-Catalyzed Asymmetric Carboalumination: Synthesis of the Scyphostatin Side Chain (I).

✍ Scribed by Ze Tan; Ei-ichi Negishi


Publisher
John Wiley and Sons
Year
2004
Weight
63 KB
Volume
35
Category
Article
ISSN
0931-7597

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An Efficient and General Method for the
✍ Ze Tan; Ei-ichi Negishi 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB 👁 1 views

We recently reported an efficient and general method for the synthesis of reduced polypropionates with a single heterofunction [1] through the application of Zr-catalyzed asymmetric carboalumination. [2, 3] In view of the large number of complex natural products that are of medicinal and biological