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An Efficient and Economical Method for the Preparation of Fmoc-Argω,ω′(Boc)2-OH

✍ Scribed by Ruixin Zhu; Ming Xie; Fei Wang; Qi Liu; Tingguo Kang

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
51 KB
Volume
28
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

The arginine derivative Fmoc‐Arg^ω,ω′^(Boc)~2~‐OH has been prepared in perfect yield starting from Fmoc‐Orn·HCl and N,N′‐di‐Boc‐N′′‐triflyguanidine with the presence of diisopropylethylamine (DIEA). This work provides an efficient and economical method for the preparation of this compound.

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