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An efficient and catalytically enantioselective route to (S)-(-)-phenyloxirane

โœ Scribed by Corey, E. J.; Shibata, Saizo; Bakshi, Raman K.


Book ID
120341425
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
457 KB
Volume
53
Category
Article
ISSN
0022-3263

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Enantioselective route to an azadirachti
โœ Hartwig Schlesiger; Ekkehard Winterfeldt ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 45 KB

An enantioselective route to the hydroxyfuran acetal substructure 36 of azadirachtin is described. The enantiopure key intermediate 29 was obtained in both absolute configurations by a kinetic resolution experiment, making use of an optical pure cyclopentadiene. After protection of the cyclopentenon