๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

An efficient 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU)-mediated synthesis of 5-(trifluoromethyl)-N-alkyl-1-(3-phenylisoquinoline-1-yl)-1H-pyrazole-4-carboxamides

โœ Scribed by K. Prabakaran; F. Nawaz Khan; Jong Sung Jin


Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
335 KB
Volume
38
Category
Article
ISSN
0922-6168

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Automated solid-phase peptide synthesis:
โœ Gavin E. Reid; Richard J. Simpson ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 955 KB

2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) has been adapted for use as a coupling reagent for tert-butyloxycarbonyl (Boc) amino acids in automated solid-phase peptide synthesis. When compared to the existing preformed symmetrical anhydride procedure employing dicycl

DAST promotes the synthesis of new 5-(tr
โœ Helio G. Bonacorso; Liliane M.F. Porte; Cleber A. Cechinel; Gisele R. Paim; Ever ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 244 KB

This study describes, firstly, the synthesis of a new precursor, 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one (1), from the trifluoroacetylation reaction of 1,1,3,3-tetramethoxybutane, in 65% yields. Afterwards, the reaction of 1 with two hydrazines (NH 2 NHR, where R = 2-furanoyl, C 6 F 5 ) led t