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An effective method for removal of the internucleotidic phenylthio group from fully protected oligonucleotides by use of bis(tributyltin) oxide

✍ Scribed by Mitsuo Sekine; Hiroshi Tanimura; Tsujiaki Hata


Book ID
104228920
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
246 KB
Volume
26
Category
Article
ISSN
0040-4039

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✦ Synopsis


Several kinds of organotin compounds involving stannyl oximates have been examined as reagents for deblocking the internucleotidic phenylthio group from an appropriately protected S-phenyl diuridine phosphorothioate (&). Among them, bis(tributyltin) oxide was found to be very effective.