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An effective formulation for an insulin suppository; examination in normal dogs

✍ Scribed by TOSHIAKI, N; MASAO, S; HIDEKI, I; AKIRA, K; TOSHIHITO, Y; RYUZO, K; MOTOAKI, S

Book ID: 122484510
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 710 KB
Volume: 38
Category: Article
ISSN: 0378-5173
DOI: 10.1016/0378-5173(87)90101-3

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## Abstract __N__‐trimethyl chitosan chloride (TMC), with degree of quaternization (DQ) of 42.77% (TMC40) and 63.03% (TMC60), respectively, were synthesized and used as absorption enhancers in an insulin rectal liquid suppository from poloxamers. The effects of the TMCs on the liquid suppository we