✦ LIBER ✦
An effective extension of the polyacetate chain in the polyene macrolide antibiotic filipin III, based on chiral oxazaborolidinone-promoted asymmetric aldol reactions
✍ Scribed by Syun-ichi Kiyooka; Mostofa A Hena; Tomomi Yabukami; Kazunori Murai; Fumitaka Goto
- Book ID
- 104210841
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 190 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The enantioselective construction of the iterative polyacetate unit 3 in filipin III has been accomplished, essentially by an aldol strategy based on chiral oxazaborolidinone-promoted asymmetric aldol reactions.