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An Effective Enantioselective Approach to the Securinega Alkaloids: Total Synthesis of (−)-Norsecurinine

✍ Scribed by Alibés, Ramón; Bayón, Pau; de March, Pedro; Figueredo, Marta; Font, Josep; García-García, Elena; González-Gálvez, David

Book ID
125896701
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
134 KB
Volume
7
Category
Article
ISSN
1523-7060

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A New Enantioselective Approach to Total
A New Enantioselective Approach to Total Synthesis of the Securinega Alkaloids: Application to (−)-Norsecurinine and Phyllanthine
✍ Gyoonhee Han; Matthew G. LaPorte; James J. Folmer; Kim M. Werner; Steven M. Wein 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB 👁 2 views

The securinega alkaloids are a family of approximately 20 tetracyclic compounds produced by several Securinega and Phyllanthus species of the Euphorbiaceae plant family. The major securinega alkaloid is securinine (1), isolated from the leaves of Securinega suffruticosa. Its enantiomer, virosecurin