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An Economic Evaluation of First-Trimester Genetic Sonography for Prenatal Detection of Down Syndrome

✍ Scribed by Anthony M Vintzileos MD; Cande V Ananth PhD; MPH; Allan J Fisher MD; John C Smulian MD; MPH; Debra Day-Salvatore MD; PhD; Tryfon Beazoglou PhD

Book ID
117192781
Publisher
Lippincott Williams and Wilkins
Year
1998
Tongue
English
Weight
361 KB
Volume
91
Category
Article
ISSN
0029-7844

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Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein ( FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE 3 ), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires