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An automated assay for the determination of asparaginase activity

✍ Scribed by Pauline F. Toncic; Donald L. Tibbetts

Book ID
119497911
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
361 KB
Volume
10
Category
Article
ISSN
0092-1157

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The antineoplastic enzyme L-asparaginase is commonly used for the induction of remission in acute lymphoblastic leukemia (ALL). There is no simple method available for measuring the activity of this highly toxic drug. We incubated L-asparaginase from Erwinia chrysanthemi with L-aspartic acid ␀-(7-am