Solid-state NMR as a probe of amyloid fi
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Robert Tycko
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Article
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2000
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Elsevier Science
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English
β 246 KB
Amyloid fibrils are intrinsically noncrystalline, insoluble, high-molecular-weight aggregates of peptides and proteins, with considerable biomedical and biophysical significance. Solid-state NMR techniques are uniquely capable of providing high-resolution, site-specific structural constraints for am