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An Atlas on Chromosomes in Hematological Malignancies. Example: 11q23 and MLL partners

โœ Scribed by Huret, J L; Dessen, P; Bernheim, A


Book ID
110054903
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
419 KB
Volume
15
Category
Article
ISSN
0887-6924

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Chromosomal analysis of acute monocytic leukemia cells in a female infant revealed a t(6;11)(q27;q23) translocation. Southern blot analysis with a cDNA probe of the MLL gene at chromosome band 11q23 indicated that the breakpoint was in an 8.3-kb BamHI fragment that contained exons 5-11 of the MLL ge