✦ LIBER ✦
An asymmetric route to fused carbocyclic systems via Diels-Alder reactions on chiral α,β-unsaturated bicyclic lactams
✍ Scribed by A.I. Meyers; Carl A. Busacca
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 196 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The cycloadducts from Diels-Alder reactions have been transformed into novel functionalized carbocycles 11 and 12 in high enantiomeric excess.
In the previous Letter,' we have described the efficient cycloaddition of various dienes to the chiral, non-racemic lactam 1. We now wish to describe the utility of these cycloadducts in providing novel and interesting fused carbocycles in high enantiomeric purity.
Two dienes, isoprene and myrcene, were chosen as examples to demonstrate the potential