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An asymmetric approach to the synthesis of trans-dihydrindandione

โœ Scribed by Keiji Yamamoto; Masayuki Iijima; Yoshinobu Ogimura; Jiro Tsuji


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
258 KB
Volume
25
Category
Article
ISSN
0040-4039

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Isoflavanones 4a-d have been prepared in a stereocontrolled fashion using (S,S)-(+)-pseudoephedrine as a chiral auxiliary. The employed synthetic pathway consists of only four steps and involves initial formation of the stereogenic centre via diastereoselective aldol reaction of pseudoephedrine aryl