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An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset Alzheimer's disease

✍ Scribed by Liana Fidani; Antonis Goulas; Richard Crook; Ronald C Petersen; Eric Tangalos; Alexandros Kotsis; John Hardy

Book ID: 116766309
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 70 KB
Volume: 357
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2003.11.071

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## Abstract The __MAPT__ gene that encodes Tau is located on chromosome 17q21, in a region, which has evolved to form two major haplotypes, H1 and H2. There is strong evidence that the H1 haplotype, and a sub‐haplotype (H1C), are overrepresented and associated with increased risk for the sporadic t