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An assessment of the skin sensitisation hazard of a group of polyfunctional silicones using a weight of evidence approach

✍ Scribed by Petry, Thomas; Bosch, Axel; Coste, Xavier; Dupuis, Valérie; Eigler, Dorothea; Germain, Pierre


Book ID
118507419
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
677 KB
Volume
64
Category
Article
ISSN
0273-2300

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✍ Claire M. Ellison; Judith C. Madden; Philip Judson; Mark T. D. Cronin 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 277 KB

## Abstract Integrated testing strategies are an important and useful approach to reduce animal usage in toxicity testing. Increased usage of integrated testing strategies is foreseen in current chemical legislation, e.g. REACH. Skin sensitisation is a well studied endpoint and many in silico model