We read with great interest the article by Azzalini et al., 1 who demonstrated that cigarette smoking worsens the severity of nonalcoholic fatty liver disease (NAFLD) in obese Zucker rats. In a related letter, Xu and coworkers 2 showed that cigarette smoking may act as a cofactor but not as an indep
An assessment of chromosomal alterations detected by fluorescence in situ hybridization and p16 expression in sporadic and primary sclerosing cholangitis-associated cholangiocarcinomas
β Scribed by Ryan D. DeHaan; Benjamin R. Kipp; Thomas C. Smyrk; Susan C. Abraham; Lewis R. Roberts; Kevin C. Halling
- Book ID
- 116534282
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 876 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1532-8392
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We read with great interest the article by Azzalini et al., 1 who demonstrated that cigarette smoking worsens the severity of nonalcoholic fatty liver disease (NAFLD) in obese Zucker rats. In a related letter, Xu and coworkers 2 showed that cigarette smoking may act as a cofactor but not as an indep
## Background: A fluorescence in situ hybridization (fish) technique using specific dna probes allows for the detection of chromosomal aberrations and gene deletions and gains, even in interphase nuclei in human solid tumors. a high frequency of aberrations of chromosome 17 and mutation of the p53