An Aptamer-Based Quartz Crystal Protein
โ
Liss, Michael; Petersen, Birgit; Wolf, Hans; Prohaska, Elke
๐
Article
๐
2002
๐
American Chemical Society
๐
English
โ 394 KB
We developed a quartz crystal biosensor designed to detect concentrations and ligand affinity parameters of free unlabeled proteins in real time. Using a model system with human IgE as the analyte and single-stranded DNA aptamers or an anti-IgE antibody as immobilized ligands, we could demonstrate t