𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An Approximate EM Algorithm for Nonlinear Mixed Effects Models

✍ Scribed by Munther Al-Zaid; Shie-Shien Yang

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
112 KB
Volume
43
Category
Article
ISSN
0323-3847

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

REML Estimation of Variance Parameters i
REML Estimation of Variance Parameters in Nonlinear Mixed Effects Models Using the SAEM Algorithm
✍ Cristian Meza; Florence JaffrΓ©zic; Jean-Louis Foulley πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 147 KB πŸ‘ 2 views

## Abstract Nonlinear mixed effects models are now widely used in biometrical studies, especially in pharmacokinetic research or for the analysis of growth traits for agricultural and laboratory species. Most of these studies, however, are often based on ML estimation procedures, which are known to

An approximation algorithm for quadratic
An approximation algorithm for quadratic cost 0–1 mixed integer programming problems
✍ Kumiko Mukai; Keiji Tatsumi; Masao Fukushima πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 586 KB

In this paper, we focus on the quadratic cost 01 mixed integer programming problem. First, we formulate the problem as a two-level programming problem that consists of a lower-level continuous quadratic programming problem with 01 variables fixed and an upper-level nonlinear 01 programming problem.

An application of nonlinear mixed-effect
An application of nonlinear mixed-effects modeling to pharmacokinetic data exhibiting nonlinear and time-dependent behavior
✍ L. Iavarone; R. Gomeni πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 154 KB

A population pharmacokinetic (PK) analysis was performed on plasma concentrations of GW468816 observed in dogs after 10, 25, and 50 mg/kg/day repeated intravenous administration. A two-compartment model was fitted to the concentration-time data using the NONMEM program. Dose and time dependency of P