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An approach to oxazolidin-2-ones from the Baylis–Hillman adducts. Formal synthesis of a chloramphenicol derivative

✍ Scribed by Fernando Coelho; Rodrigo C Rossi

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
147 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

In this communication we describe a straightforward and diastereoselective approach to prepare functionalised oxazolidin-2-ones from Baylis-Hillman adducts. A stereoselective synthesis of a highly substituted vicinal aminoalcohol and a formal synthesis of a chloramphenicol derivative are also described.

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