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An application of changepoint methods in studying the effect of age on survival in breast cancer

✍ Scribed by Cécile Contal; John O'Quigley

Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
300 KB
Volume
30
Category
Article
ISSN
0167-9473

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✦ Synopsis

The role of age in prognostic studies in breast cancer remains to be clearly established. There is reasonable agreement that younger patients have higher risk of an unfavorable outcome but there is little agreement on the precise nature of the relationship between age and prognosis. A ÿrst step in studying any such relationship can be based on the division of patients into two groups: a high risk and a low risk group. A simple and popular classiÿcation rule consists in determining a cuto value of the continuous variable age. How to choose the actual cuto however is not a straightforward problem (

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