𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An apoptosis-independent role of SMAC in tumor suppression

✍ Scribed by Qiu, W; Liu, H; Sebastini, A; Sun, Q; Wang, H; Zhang, L; Yu, J

Book ID
118004340
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
736 KB
Volume
32
Category
Article
ISSN
0950-9232

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## Abstract Tumors frequently acquire resistance to apoptosis that is expected to contribute to malignant phenotype and reduce sensitivity to treatment. In fact, inactivation of __p53__ tumor suppressor gene resulting in suppression of apoptosis serves as a negative prognostic marker. Surprisingly,