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An analysis of the relationship between radiosensitivity and volume effects in tumor control probability modeling

✍ Scribed by Buffa, Francesca M.; Fenwick, John D.; Nahum, Alan E.

Book ID
120274704
Publisher
American Institute of Physics
Year
2000
Tongue
English
Weight
93 KB
Volume
27
Category
Article
ISSN
0094-2405

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## Abstract Wortmannin (WM) is a potent inhibitor of the catalytic sub‐unit of DNA‐PK, which is involved in one pathway of DNA double‐strand break (DSB) rejoining, and of ATM, which functions upstream in the p53 signaling pathway. WM is known to be an efficient radiosensitizer in a variety of mamma