An analysis of the pharmacokinetic parameter ratios in DCE-MRI using the reference region model
✍ Scribed by Joonsang Lee; Simon Platt; Marc Kent; Qun Zhao
- Book ID
- 113809716
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 969 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0730-725X
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## Abstract Models have been developed for analyzing dynamic contrast‐enhanced (DCE)‐MRI data that do not require measurements of the arterial input function (AIF). In this study, experimental results obtained from a reference region (RR) analysis are compared with results of an AIF analysis in the
In dynamic contrast-enhanced MR imaging (DCE-MRI), sampling of the arterial input function (AIF) is required for analysis using the general kinetic model (GKM). Alternatively, the recently proposed reference region model (RRM) may be employed to avoid the need of acquiring the AIF. This study aimed