## Abstract ^13^C NMR spectra of six epimeric substituted 4‐hydroxypiperidines and two corresponding piperidines were recorded. Substituent parameters for equatorial methyl, __gem__‐dimethyl, equatorial hydroxy and axial hydroxy groups were calculated from the ^13^C chemical shifts of these compoun
✦ LIBER ✦
An Analysis of Substituent Effects on the Proton and Carbon-13 Chemical Shifts of 9-Chloro and 9-Amino Acridines
✍ Scribed by Robert Faure; Jean-Pierre Galzy; Jacques Barbe; Abdel Lhatif Boukir; Emile-Jean Vincent; Gérard Boyer; José Elguero
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 354 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0037-9646
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The 13 C chemical shifts of the title compounds (1) were determined in CDCl 3 and in CD 3 OD as well as in D 2 SO 4 solutions. Moreover 17 O chemical shifts of 1 in CDCl 3 were measured. The SCS (substituent-induced chemical shift) values were analyzed by means of linear free energy (LFE) relationsh