An amphiphilic fluorescent probe for the visualization of histamine in living cells

✍ Scribed by Daisuke Seto; Nobuaki Soh; Koji Nakano; Toshihiko Imato

• Book ID: 104004865
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 642 KB
• Volume: 20
• Category: Article
• ISSN: 0960-894X
• DOI: 10.1016/j.bmcl.2010.09.003

✦ Synopsis

A novel fluorescent probe composed of two moieties, Nile Red and an iminodiacetic acid-Ni 2+ complex, for the detection of histamine in living cells is described. The probe was successfully applied to visualizing histamine in RAW264 cells, representing the first demonstration of the imaging of histamine itself in living cells.