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An Amperometric Cellobiose Dehydrogenase-Based Biosensor Can Be Used for Measurement of Cellulase Activity

✍ Scribed by Lars Hildén; Lars Eng; Gunnar Johansson; Sten-Eric Lindqvist; Göran Pettersson


Book ID
102566608
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
117 KB
Volume
290
Category
Article
ISSN
0003-2697

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✦ Synopsis


The hemoflavoenzyme cellobiose dehydrogenase (CDH, EC 1.1.99.18) from Phanerochaete chrysosporium has been used in an amperometric redox polymer-based biosensor. Used in conjugation with a FIA system this biosensor can replace colorimetric assays for measuring cellobiose liberated from cellulose in a series of cellulase-containing samples. The biosensor gave the same result as the Somogyi-Nelson method in a less time-consuming and laborious manner. The two methods showed about the same precision.