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An Ambiguity in the Variable-Solvent Solubility Test: Homogeneity of β1-Lactoglobulin

✍ Scribed by OGSTON, A. G.; TOMBS, M. P.


Book ID
109590169
Publisher
Nature Publishing Group
Year
1956
Tongue
English
Weight
156 KB
Volume
178
Category
Article
ISSN
0028-0836

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The antibody MAB007 was recently shown to be cysteinylated on an unpaired cysteine residue in the CDR3 variable region. Cysteinylation at this position was not complete and resulted in heterogeneous lots of MAB007 with respect to this posttranslational modification. In this report, a mild redox step