An Alternative to Tandem Mass Spectrometry: Isoelectric Point and Accurate Mass for the Identification of Peptides
β Scribed by Cargile, Benjamin J.; Stephenson, James L.
- Book ID
- 127048422
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 200 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0003-2700
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Synthetic proteins with unusual architecture are obtained through chemoselective ligation, a method based on the condensation of unprotected peptides under mild aqueous conditions. The last step of a new procedure leading to a tri-branched conjugate consists of the chemoselective ligation reaction b
The limitations of conventional gas chromatography-mass spectrometry (GC-MS) analyses for alkyl-and aryl-tin compounds are discussed, particularly the excessive fragmentation from electron impact (EI) ionization. Negative EI methods exhibit low ionization capabilities and are restricted to compounds
Structure identification strategies for kedarcidin chromophore are described using tandem mass spectrometry (MS/MS) and high-resolution MS techniques. The strategy involves dividing a large, complex natural product molecule into several smaller molecules (substructures) to simplify identification. S