An alternative substrate is not the same as a dead end inhibitor

Cell adhesion to agrin presented as a na

Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules

✍ Tobias Wolfram; Joachim P Spatz; Robert W Burgess 📂 Article 📅 2008 🏛 BioMed Central 🌐 English ⚖ 547 KB

## Background Molecular spacing is important for cell adhesion in a number of ways, ranging from the ordered arrangement of matrix polymers extracellularly, to steric hindrance of adhesion/signaling complexes intracellularly. This has been demonstrated using nanopatterned RGD peptides, a canonical