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An alternative method for calculating simple pharmacokinetic parameters for zero-order absorption and first-order elimination processes

✍ Scribed by Meir Bialer

Book ID: 101701314
Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 200 KB
Volume: 2
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.2510020404

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✦ Synopsis

Abstract

An alternative way to the classical method is presented for calculating the relevant pharmacokinetic parameters for zero‐order absorption and first‐order elimination processes. Although the equations were derived using the one compartment body model, some of them are applicable to the multicomponent body model as well. The method presented is useful whether or not a steady state is reached.

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