An alternative index for assessing profile similarity in bioequivalence trials

AN INDEX FOR ASSESSING BLINDNESS IN A MU

AN INDEX FOR ASSESSING BLINDNESS IN A MULTI-CENTRE CLINICAL TRIAL: DISULFIRAM FOR ALCOHOL CESSATION—A VA COOPERATIVE STUDY

✍ KENNETH E. JAMES; DANIEL A. BLOCH; KELVIN K. LEE; HELENA C. KRAEMER; RICHARD K. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 819 KB

This paper considers an index to assess the success of blinding with application to a clinical trial of disulfiram. The index increases as the success of blinding increases, accounts for uncertain responses, and is scaled to an interval of 0 0 to 1.40-0 being complete lack of blinding and 1.0 being