Tumors need to acquire an angiogenic phenotype for outgrowth and metastasis formation. Limited information on the angiogenic potential of specific tissues, especially human breast tissues is available. Here we describe an in vivo model, using the dorsal skin fold chamber in immunodeficient nude mice
β¦ LIBER β¦
An alternative in vivo system for testing angiogenic potential of human neuroblastoma cells
β Scribed by Domenica Mangieri; Beatrice Nico; Addolorata M.L. Coluccia; Angelo Vacca; Mirco Ponzoni; Domenico Ribatti
- Book ID
- 116335094
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 365 KB
- Volume
- 277
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Neuroblastoma is the most common type of cancer in infants. In children this tumor is particularly aggressive; despite various new therapeutic approaches, it is associated with poor prognosis. Given the importance of endosomalβlysosomal proteolysis in cellular metabolism, we hypothesize