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An alternative branch of the nonsense-mediated decay pathway

✍ Scribed by Chan, Wai-Kin; Huang, Lulu; Gudikote, Jayanthi P; Chang, Yao-Fu; Imam, J Saadi; MacLean, James A; Wilkinson, Miles F


Book ID
110032001
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
519 KB
Volume
26
Category
Article
ISSN
0261-4189

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Inhibition of nonsense-mediated mRNA dec
✍ Fusako Usuki; Akio Yamashita; Itsuro Higuchi; Tetsuo Ohnishi; Tadafumi Shiraishi πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 570 KB

## Abstract Nonsense‐mediated mRNA decay (NMD) is an mRNA surveillance system that eliminates aberrant mRNAs containing premature translation termination codons (PTCs). We evaluated the role of NMD in of Ullrich's disease. The patient has a frameshift mutation with a PTC in the collagen VI Ξ±2 gene