𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An alternate synthesis of enantiomerically pure levetiracetam (Keppra®)

✍ Scribed by M. Mujahid; P. Mujumdar; M. Sasikumar; S.S. Kunte; M. Muthukrishnan


Book ID
118002050
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
391 KB
Volume
23
Category
Article
ISSN
0957-4166

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


An alternate synthesis of levetiracetam
✍ Mylavarapu, Ravikumar; Anand, Ramasamy Vijaya; Kondaiah, Golla China Mala; Reddy 📂 Article 📅 2010 🏛 Taylor and Francis Group 🌐 English ⚖ 164 KB
Synthesis of enantiomerically pure indol
✍ Shiqi, Peng ;Li, Zhang ;Mengshen, Cai ;Winterfeldt, Ekkehard 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 612 KB

## Abstract L‐Tryptophan methyl ester reacts with 1,1,3,3‐tetramethoxypropane to give methyl carbolinecarboxylate 2 as a 1:2 mixture of the (1__R__,3__S__) and (1__S__,3__S__) stereoisomers. Conversion to the corresponding amides (1__R__,3__S__)‐3 and (1__S__,3__S__)‐3 was accomplished by treatment