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An Allenic Pauson–Khand Approach to 6,12-Guaianolides

✍ Scribed by Grillet, Francois; Huang, Chaofeng; Brummond, Kay M.


Book ID
120394664
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
925 KB
Volume
13
Category
Article
ISSN
1523-7060

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📜 SIMILAR VOLUMES


An intramolecular Pauson–Khand approach
✍ Ramon Rios; Albert Moyano; Miquel A Pericàs 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 98 KB

A procedure for the synthesis of chirally-substituted cyclopentadienes has been developed by employing the intramolecular Pauson-Khand reaction of chiral amides derived from 8-nonen-2-ynoic acid. Hydride-mediated reduction of the resulting cyclopentenone adducts followed by acid-catalysed dehydratio