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An algebraic model of RNA duplex formation

✍ Scribed by J. D. Bashford; P. D. Jarvis


Publisher
Wiley (John Wiley & Sons)
Year
2004
Tongue
English
Weight
127 KB
Volume
73
Category
Article
ISSN
0006-3525

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✦ Synopsis


Abstract

We propose a simple algebraic description of the two‐body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest‐neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containing Watson–Crick pairs, fits to oligonucleotide duplex heat‐of‐formation data are shown to be statistically equivalent to existing models. © 2004 Wiley Periodicals, Inc. Biopolymers, 2004


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