An aggressive approach to marginally resectable lung cancer

✍ Scribed by David M. Sherman; Wilford Neptune; Ralph Weichselbaum; Stanley E. Order; Anthony J. Piro

• Book ID: 101327400
• Publisher: John Wiley and Sons
• Year: 1978
• Tongue: English
• Weight: 461 KB
• Volume: 41
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197805)41:5<2040::aid-cncr2820410552>3.0.co;2-i

✦ Synopsis

patients with lung cancer were planned for preoperative irradiation and surgery. All patients were cdnsidered clinically marginally resectable because of advanced local disease, 4 Stage I1 patients, with limited pulmonary reserve and 49 Stage 111 patients. Most patients received 3000 to 4000 rad followed in two weeks by thoracotomy. Fortysix patients were explored and 38 were resectable. Twelve patients are alive with a median follow-up of 48 months. The cumulative 5-year survival of all resectable patients is 27%. The survival of patients with marginally resectable lung cancer treated by accelerated radiotherapy followed bp aggressive surgery approaches the survival experience of patients with primary resectable lung cancer and is superior to such patients treated with radiation therapy alone.