An adenoviral vector-based mucosal vaccine is effective in protection against botulism

A single immunization with a minute dose

A single immunization with a minute dose of a lentiviral vector-based vaccine is highly effective at eliciting protective humoral immunity against West Nile virus

✍ Maria Candela Iglesias; Marie-Pascale Frenkiel; Karine Mollier; Philippe Souque; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 296 KB

## Abstract ## Background Lentiviral vectors, due to their capacity to transduce non‐dividing cells, have become precious and worldwide used gene transfer systems. Their ability to efficiently and stably transduce dendritic cells (DCs) has led to their successful use as vaccination vectors for eli