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An adenosine kinase mutation in baby hamster kidney cells causing increased sensitivity to adenosine

✍ Scribed by P. Juranka; F. Meffe; S. Guttman; S.M. Archer; V.L. Chan

Book ID: 113192683
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 436 KB
Volume: 129
Category: Article
ISSN: 0027-5107
DOI: 10.1016/0027-5107(84)90095-2

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## Abstract Analysis of the response of baby hamster kidney cells to adenosine in the presence of the adenosine deaminase inhibitor erythro‐9‐(2‐hydroxy‐3‐nonyl) adenine has revealed two distinct mechanisms of toxicity. The first is apparent at low concentrations of adenosine (< 5 μM) and is depend