An activated catalyst RhH(PPh3)4-dppe- Me2S2 for α-methylthiolaton of α-phenyl ketones

✍ Scribed by Mieko Arisawa; Fumihiko Toriyama; Masahiko Yamaguchi

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 252 KB
• Volume: 22
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20650

✦ Synopsis

Abstract

In the presence of catalytic amounts of RhH(PPh~3~)~4~, 1,2‐bis(diphenylphosphino)ethane (dppe), and dimethyl disulfide, cyclic and acyclic α‐phenyl ketones reacted with p‐cyano‐α‐methylthioa‐ cetophenone giving α‐methylthio‐α‐phenylketones. The activated catalyst containing dimethyl disulfide was effective for the α‐methylthiolation reaction of these less reactive substrates. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 22:18–23, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20650