✦ LIBER ✦

An acid phosphatase locus expressed in mouse kidney (Apk) and its genetic location on chromosome 10

✍ Scribed by James E. Womack; Sandra Belsky Auerbach

Publisher: Springer
Year: 1978
Tongue: English
Weight: 332 KB
Volume: 16
Category: Article
ISSN: 0006-2928
DOI: 10.1007/bf00484081

No coin nor oath required. For personal study only.

✦ Synopsis

A genetic locus controlling the electrophoretic mobility of an acid phosphatase in mouse kidney is described. This locus, called acid phosphatase-kidney (Apk), is not expressed in erythrocytes, liver, spleen, heart, lung, brain, skeletal muscle, stomach, or testes. The product of Apk hydrolyzes the substrate naphthol AS-MX phosphoric acid but is not active on alpha-naphthylphosphate or 4-methylumbelliferylphosphate. It is not inactivated by 50 C for 1 hr, nor is its electrophoretic mobility altered by incubation with neuraminidase. The locus is invariant among 31 inbred strains (Apka), with a variant allele (Apkm) observed only in Mus musculus molossinus. Codominant expression was observed in F1 hybrids of M. m. molossinus and inbred strains. Apk was mapped on Chr 10, near the neurological mutant waltzer (v).

📜 SIMILAR VOLUMES

Esterase 13, a new mouse esterase locus

Esterase 13, a new mouse esterase locus with recessive expression and its genetic location on chromosome 9

✍ James E. Womack; Benjamin A. Taylor; Joan E. Barton 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 276 KB

A new esterase locus (Es-13) has been identified in Musculus. Strains AEJ/GnRk, LG/J, SJL/J, and SWR/J carry a recessive allele, Es-13b, for a locus possibly involved in the posttranslational modification of a kidney esterase. All other strains observed carried the dominant Es-13a allele. Es-13 was

Genetic variation of an intestinal leuci

Genetic variation of an intestinal leucine arylaminopeptidase (Lap-1) in the mouse and its location on chromosome 9

✍ James E. Womack; Michael A. Lynes; Benjamin A. Taylor 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 403 KB

Electrophoretic variation for an intestinal enzyme that cleaves L-leucyl-beta-naphthylamide has been discovered among inbred mouse strains. Several strains including related strains C57BL/6J, C57BL/10J, C57BR/cdJ, C57L/J, and C58/J demonstrate an electrophoretic band of this enzyme that is absent in