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An abnormal form of purine nucleoside phosphorylase in a family with a child with severe defective T-cell-and normal B-cell immunity

โœ Scribed by L.H.Siegenbeek Van Heukelom; G.E.J. Staal; J.W. Stoop; B.J.M. Zegers


Book ID
115821034
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
793 KB
Volume
72
Category
Article
ISSN
0009-8981

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Incorporation of purine nucleosides in c
โœ Wylie G. Burke; Shi-Han Chen; C. Ronald Scott; Arthur J. Ammann Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 396 KB

## Abstract Cultured skin fibroblasts from a patient with Tโ€cell immune deficiency and an absence of purine nucleoside phosphorylase activity in red cells were assayed for their capacity to metabolize inosine and guanosine. The cultured fibroblasts were lacking activity of nucleoside phosphorylase