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Amyotrophic lateral sclerosis mimic syndrome due to a dorsal spinal cord neurofibroma

✍ Scribed by Andrea Calvo; Franco Benech; Paolo Ghiglione; Michele Balma; Cristina Moglia; Roberto Mutani; Adriano Chiò


Book ID
106268810
Publisher
Springer Milan
Year
2009
Tongue
English
Weight
151 KB
Volume
31
Category
Article
ISSN
1590-1874

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## Abstract Microglial activation occurs early during the pathogenesis of amyotrophic lateral sclerosis (ALS). Recent evidence indicates that the expression of mutant Cu^2+^/Zn^2+^ superoxide dismutase 1 (SOD1) in microglia contributes to the late disease progression of ALS. However, the mechanism