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Amyotrophic lateral sclerosis immunoglobulins increase Ca2+ currents in a motoneuron cell line

โœ Scribed by Dr. Dennis R. Mosier; Pietro Baldelli; Osvaldo Delbono; R. Glenn Smith; Maria E. Alexianu; Stanley H. Appel; Enrico Stefani


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
783 KB
Volume
37
Category
Article
ISSN
0364-5134

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Retinoic acid inhibits Ca2+ currents and
โœ Martha Bosma; Neil Sidell ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 645 KB

Using the whole-cell variation of the patch-clamp technique, we have demonstrated that retinoic acid (RA) blocks Ca channels and inhibits cell proliferation in a mouse hybridoma cell line (MHY206) derived from a fusion of murine myeloma and splenic B cells. In 25 mM external Ca, and with an Na inter