Although amyloidosis may complicate many chronic inflammatory arthropathies including rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis ( I ) , its association with gout is extremely rare ( 2 ) . We report here a patient with amyloidosis secondary to poiyarticular gout in whom amyloid A protein (AA) was demonstrated in the walls of amyloid-laden blood vessels. Colchicine therapy resulted in prevention of further attacks of gout, improvement in renal function, decrease in proteinuria, and restoration of serum albumin to normal.
Case Report. An 85-year-old man was admitted to the hospital because of acute polyarthritis primarily affecting his elbows and distal interphalangeal (DIP) joints. During the previous 10 years, he had suffered from recurrent attacks of gout. He received indomethacin for these acute episodes, but he was noncompliant regarding medications prescribed for lowering his serum uric acid. Apart from these attacks, he was well and denied any previous illnesses, including tuberculosis, osteomyelitis, or any other chronic infectious or inflammatory disease. The physical examination was unremarkable except for severe tenderness, swelling, and diminished range of motion in his elbows From the