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Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme

✍ Scribed by Igor V Kurochkin


Book ID
117109097
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
94 KB
Volume
427
Category
Article
ISSN
0014-5793

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The recently identified 53-kDa substrate of the insulin receptor family was further characterized in several retroviral-generated stable cell lines overexpressing the wild type and various mutant forms of the protein. To facilitate the study of its subcellular localization in NIH3T3 cells overexpres