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Amyloid β-Protein: The Influence of Intrinsic and Extrinsic Factors on Fibril Formation

✍ Scribed by Cukalevski, Risto; Yang, Xiaoting; Cohen, Samuel; Boland, Barry; Frohm, Birgitta; Thulin, Eva; Walsh, Dominic; Knowles, Tuomas; Linse, Sara

Book ID
122870067
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
155 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract Macromolecular crowding is expected to have several significant effects on protein aggregation; the major effects will be those due to excluded volume and increased viscosity. In this report we summarize data demonstrating that macromolecular crowding may lead to a dramatic acceleration