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Amyloid precursor protein binding protein-1 modulates cell cycle progression of neural stem cells

✍ Scribed by Kim, Hee Jin; Joo, Yuyoung; Hong, Bo-Hyun; Ha, Sungji; Kim, Jeong-A; Chang, Keun-A; Woong, Sun; Lee, Sang Hyung; Suh, Yoo-Hun; Kim, Hye-Sun

Book ID
121910604
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
43 KB
Volume
68
Category
Article
ISSN
0168-0102

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## Abstract Apolipoprotein E4 (apoE4) genotype is associated with an increased risk for Alzheimer's disease (AD). This is thought to be in part attributable to an impact of apoE genotype on the processing of the transmembrane amyloid precursor protein (APP) thereby contributing to amyloid beta pept